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Pancreatic Ductal Adenocarcinoma DFP

DFP Profile

DFP NAME:

Pancreatic Ductal Adenocarcinoma

 

DFP MISSION:

To improve the care of patients with pancreatic cancer through imaging with initiatives to improve communication between radiology and other clinical specialties, and to perform research and facilitate implementation of best practices for the detection, diagnosis, staging, and monitoring of treatment response for this disease.

 

DFP GOALS:

  1. To increase interdisciplinary discussion and interaction to improve imaging diagnosis and management of pancreatic ductal adenocarcinoma.
  2. To educate the panel members, and ultimately the society as a whole, of the important topics of pancreatic cancer.
  3. To develop and execute radiology specific multidisciplinary and multi-institutional research initiatives to enhance early diagnosis of pancreatic cancer and monitor response to local and systemic therapy.

 

SAR Pancreatic Ductal Adenocarcinoma DFP Members:

Eric Tamm, MD

Avinash Kambadakone-Ramesh, MD, FRCR

Alexander Guimaraes, MD, PhD

Priya Bhosale, MD

Arnold Friedman, MD

Atif Zaheer, MD

Erik Soloff, MD

Jason Fleming, MD, FACS

David Hough, MD

Mannelli Lorenzo, MD

Ott Le, MD

Siva Raman, MD
Guillermo P. Sangster, MD

Zarine Shah, MD

 

Lead Consultant:

Jason Fleming, MD

 

DFP Leadership:

Eric Tamm, MD, Chair

Avinash Kambadakone-Ramesh, MD, FRCR, Co-Chair

 

Short-Term Goals:

1. Education

The educational objectives of the panel would include discussion of conventional radiology topics such as current best practices for imaging of pancreatic cancer comprising of CT, MRI and PET/CT and the incorporation of technologies such as endoscopic ultrasound into the workflow of diagnosing and staging pancreatic cancer. The role of imaging in clinically pertinent areas such as identification of recurrence, monitoring of treatment response and management of complications of treatment will be also be discussed. The short term educational goals would be accomplished through a combination of educational initiatives as outlined below:

a. Lectures and/or workshops at the annual SAR meeting and review articles in Abdominal Radiology.

b. Lectures/ workshops at other major radiology and non-radiology national conferences (SAR, RSNA, ISMRM, ARRS, ASCO, DDW). 

c. Regular webinars or WebEx lectures throughout the year (proposed goal – 4-6/year). The content of the webinars will expand on the scope of topics regularly delivered at the annual meeting. The format of the webinars would be structured as lectures and/or workshops that will aim to bring to the Society knowledge of the greater outer world of pancreatic cancer as experienced by our colleagues in surgical oncology, medical oncology, radiation oncology, and gastroenterology and the current state-of-the-art of research. 


2. Research:

a. Multi-center imaging trials/projects for further development of imaging and its role in pancreatic cancer. In the first year, we anticipate choosing topics, setting up ground work (choosing project lead/PIs, submitting and getting approval of institutional IRB requests, etc.), determining feasibility, and initiating the research process.

b. To work with the Pancreatic Cancer Action Network (PanCAN) to develop an image repository. The goal would be to have patients contribute their imaging to this database. This could fit together with image initiatives from the SAR, and would provide a platform for correlation between radiology and such data as may be obtained from research projects sponsored by PanCAN.

c. To assess the current state of knowledge with regard to imaging biomarkers of subtypes of pancreatic cancer, and to assess the significance of these findings with regard to prognoses in a multi-institution setting.

d. To study the value of imaging in identifying response to neoadjuvant chemo-radiation in patients with borderline and locally advanced pancreatic cancer prior to surgical resection. The intent would be particularly to look for the ability of advanced imaging techniques such as dual energy CT, diffusion weighted MR imaging and newer molecular agents (PET) in detection of residual tumor.


3. Creation of resources for the society:

a. Creation of a webpage to host radiology report templates and contain links to relevant websites such as RSNA as well as to pancreas specific societies and relevant resources from specialties outside of radiology.

b. To work with the Society on the already ongoing project of an image platform that would allow for central storage and remote review of images for the purpose of multi-institutional projects.

c. To work with the Society to develop a web portal for access to clinical, educational, and research resources. This would include access to societies focused on pancreatic cancer (PanCAN, American Pancreatic Association, Lustgarten Society), radiology reporting templates, etc.

 


 

Member Resources


Pancreatic ductal adenocarcinoma radiology reporting template: consensus statement of the society of abdominal radiology and the american pancreatic association.


http://www.ncbi.nlm.nih.gov/pubmed/24355035


http://www.ncbi.nlm.nih.gov/pubmed/24354378


Kulkarni NM, Mannelli L, Zins M, et al. White paper on pancreatic ductal adenocarcinoma from society of abdominal radiology's disease-focused panel for pancreatic ductal adenocarcinoma: Part II, update on imaging techniques and screening of pancreatic cancer in high-risk individuals. Abdom Radiol (NY). 2020;45(3):729-42.

Kulkarni NM, Soloff EV, Tolat PP, et al. White paper on pancreatic ductal adenocarcinoma from society of abdominal radiology's disease-focused panel for pancreatic ductal adenocarcinoma: Part I, AJCC staging system, NCCN guidelines, and borderline resectable disease. Abdom Radiol (NY). 2020;45(3):716-28.

Baliyan V, Kordbacheh H, Parakh A, Kambadakone A. Response assessment in pancreatic ductal adenocarcinoma: role of imaging. Abdom Radiol (NY). 2018;43(2):435-44.

Bhalla M, Aldakkak M, Kulkarni NM, et al. Characterizing indeterminate liver lesions in patients with localized pancreatic cancer at the time of diagnosis. Abdom Radiol (NY). 2018;43(2):351-63.

Bhattacharya A, Gandhi NS, Baker ME, Chahal P. Gastroenterology and pancreatic adenocarcinoma: what the radiologist needs to know. Abdom Radiol (NY). 2018;43(2):364-73.

Bhosale P, Cox V, Faria S, et al. Genetics of pancreatic cancer and implications for therapy. Abdom Radiol (NY). 2018;43(2):404-14.

Camacho A, Fang J, Cohen MP, Raptopoulos V, Brook OR. Split-bolus pancreas CTA protocol for local staging of pancreatic cancer and detection and characterization of liver lesions. Abdom Radiol (NY). 2018;43(2):340-50.

Fogelman DR, Varadhachary G. Medical oncology and pancreatic cancer: what the radiologist needs to know. Abdom Radiol (NY). 2018;43(2):383-92.

Fonseca AL, Fleming JB. Surgery for pancreatic cancer: critical radiologic findings for clinical decision making. Abdom Radiol (NY). 2018;43(2):374-82.

Gandhi NS, Feldman MK, Le O, Morris-Stiff G. Imaging mimics of pancreatic ductal adenocarcinoma. Abdom Radiol (NY). 2018;43(2):273-84.

Garces-Descovich A, Beker K, Jaramillo-Cardoso A, James Moser A, Mortele KJ. Applicability of current NCCN Guidelines for pancreatic adenocarcinoma resectability: analysis and pitfalls. Abdom Radiol (NY). 2018;43(2):314-22.

Hafezi-Nejad N, Fishman EK, Zaheer A. Imaging of post-operative pancreas and complications after pancreatic adenocarcinoma resection. Abdom Radiol (NY). 2018;43(2):476-88.

Javadi S, Karbasian N, Bhosale P, et al. Imaging findings of recurrent pancreatic cancer following resection. Abdom Radiol (NY). 2018;43(2):489-96.

Javed AA, Bleich K, Bagante F, et al. Pancreaticoduodenectomy with venous resection and reconstruction: current surgical techniques and associated postoperative imaging findings. Abdom Radiol (NY). 2018;43(5):1193-203.

Kambadakone AR, Zaheer A, Le O, et al. Multi-institutional survey on imaging practice patterns in pancreatic ductal adenocarcinoma. Abdom Radiol (NY). 2018;43(2):245-52.

Kawamoto S, Fuld MK, Laheru D, Huang P, Fishman EK. Assessment of iodine uptake by pancreatic cancer following chemotherapy using dual-energy CT. Abdom Radiol (NY). 2018;43(2):445-56.

Koay EJ, Hall W, Park PC, Erickson B, Herman JM. The role of imaging in the clinical practice of radiation oncology for pancreatic cancer. Abdom Radiol (NY). 2018;43(2):393-403.

Kulkarni NM, Hough DM, Tolat PP, Soloff EV, Kambadakone AR. Pancreatic adenocarcinoma: cross-sectional imaging techniques. Abdom Radiol (NY). 2018;43(2):253-63.

Lindquist CM, Miller FH, Hammond NA, Nikolaidis P. Pancreatic cancer screening. Abdom Radiol (NY). 2018;43(2):264-72.

Parakh A, Patino M, Muenzel D, Kambadakone A, Sahani DV. Role of rapid kV-switching dual-energy CT in assessment of post-surgical local recurrence of pancreatic adenocarcinoma. Abdom Radiol (NY). 2018;43(2):497-504.

Patel BN, Olcott E, Jeffrey RB. Extrapancreatic perineural invasion in pancreatic adenocarcinoma. Abdom Radiol (NY). 2018;43(2):323-31.

Patel BN, Olcott EW, Jeffrey RB. Duodenal invasion by pancreatic adenocarcinoma: MDCT diagnosis of an aggressive imaging phenotype and its clinical implications. Abdom Radiol (NY). 2018;43(2):332-9.

Rashid MF, Hecht EM, Steinman JA, Kluger MD. Irreversible electroporation of pancreatic adenocarcinoma: a primer for the radiologist. Abdom Radiol (NY). 2018;43(2):457-66.

Rayamajhi S, Balachandran A, Katz M, Reddy A, Rohren E, Bhosale P. Utility of (18) F-FDG PET/CT and CECT in conjunction with serum CA 19-9 for detecting recurrent pancreatic adenocarcinoma. Abdom Radiol (NY). 2018;43(2):505-13.

Soloff EV, Zaheer A, Meier J, Zins M, Tamm EP. Staging of pancreatic cancer: resectable, borderline resectable, and unresectable disease. Abdom Radiol (NY). 2018;43(2):301-13.

Steinman J, Zaheer A, Kluger MD, Remotti H, Hecht EM. Rare pancreatic tumors. Abdom Radiol (NY). 2018;43(2):285-300.

Tamm EP. Introduction to the special section on pancreatic cancer. Abdom Radiol (NY). 2018;43(2):243-4.

Vergauwen MAT, Perillo M, Garces-Descovich A, Barrows CE, Moser AJ, Mortele KJ. Radiologic evaluation of patients undergoing the modified Appleby procedure for locally advanced pancreatic neoplasms: a case series. Abdom Radiol (NY). 2018;43(2):467-75.

Yeh R, Dercle L, Garg I, Wang ZJ, Hough DM, Goenka AH. The Role of 18F-FDG PET/CT and PET/MRI in Pancreatic Ductal Adenocarcinoma. Abdom Radiol (NY). 2018;43(2):415-34.

 
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